Probiotics to suit your needs – New products from Colfarm

A new brand of probiotics, Biotilac, has been added to Colfarm’s product portfolio. It is represented by 5 unique variants that respond to different patient needs.

Although the beneficial effects of probiotic bacteria have been exploited for hundreds or even thousands of years, and the conscious use of probiotic bacteria for therapeutic purposes took place as early as the beginning of the 20th century, interest in their widespread use has increased significantly in recent years in particular. It turns out that the micro-organisms that make up the intestinal bacterial flora not only play a role in the process of food digestion, but also reduce fat and cholesterol levels, alleviate the symptoms of food allergies, remove toxic substances from the blood and can even produce vitamins that are crucial to the body. ^{[ 1 ] [ 2 ] [ 3 ] [ 4 ]}

That is why, at Colfarm SA, we have been engaged for many months in developing innovative probiotics that support the human microbiome according to its individual needs. Thanks to the work of our R&D centre, we have created 5 probiotic products under the Biotilac brand, containing unique compositions of live bacterial cultures. These include:

• Biotilac BIOTIC – a multi-strain product containing 10 billion bacterial cultures per capsule to support the functioning of the body
• Biotilac IBSin – a multi-strain product containing 10 billion bacterial cultures per capsule to help relieve bowel syndrome disorders
• Biotilac HEPA – a multi-strain product containing 4 billion bacterial cultures per capsule dedicated to liver protection.
• Biotilac CHOLESTEROL – a multi-strain product containing 3 billion bacterial cultures per capsule affecting serum cholesterol levels.
• Biotilac UREA – a multi-strain product containing 3 billion bacterial cultures per capsule dedicated to the protection of the urinary tract.

Modern manufacturing technology

Beneficial bacteria, which are supplied to the body in the form of commonly used probiotic products, are very sensitive to external factors such as heat, moisture or oxygen. In addition, once ingested, they are exposed to digestive enzymes, low pH of gastric juice and bile acid salts. As a result, the bacteria may die prematurely, thus failing to show a therapeutic effect.

Biotilac capsules use state-of-the-art manufacturing technology to increase the survival rate and effectiveness of probiotics. The probiotic bacteria in BIOTILAC capsules are uniquely protected by using several dedicated technologies simultaneously:

• Microencapsulation, a technology for coating bacterial strains with protective compounds. Microencapsulation serves to increase the stability and survival of probiotic strains by protecting them from adverse physicochemical factors.
• The combination of probiotics with prebiotics (soluble, natural fibres derived from acacia – Fibregum BTM and InaveaTM), which nourish the bacteria, increasing their viability and ability to colonise.
• The use of the innovative DRcaps delayed-release capsule allows the probiotics to be released further down the digestive tract, gaining additional protection from gastric acids.

The triple protection used allows the bacteria to safely reach and populate the mucosa at the target site – the small and large intestines – so that they can support the functioning of the body.

Biotilac products are now available from wholesalers and online pharmacies.

Literature:

1. Xiaoran Song, Yanan Liu, Xin Zhang, Peifang Weng, Ruilin Zhang, Zufang Wu, Role of intestinal probiotics in the modulation of lipid metabolism: implications for therapeutic treatments, Food Science and Human Wellness, Volume 12, Issue 5, 2023, Pages 1439-1449
2. Zhang GQ, Hu HJ, Liu CY, Zhang Q, Shakya S, Li ZY. Probiotics for Prevention of Atopy and Food Hypersensitivity in Early Childhood: A PRISMA-Compliant Systematic Review and Meta-Analysis of Randomized Controlled Trials. Medicine (Baltimore). 2016 Feb;95(8):e2562. doi: 10.1097/MD.0000000000002562. PMID: 26937896; PMCID: PMC4778993.
3. Baralić K, Živančević K, Bozic D, Đukić-Ćosić D. Probiotic cultures as a potential protective strategy against the toxicity of environmentally relevant chemicals: State-of-the-art knowledge. Food Chem Toxicol. 2023 Feb;172:113582. doi: 10.1016/j.fct.2022.113582. Epub 2022 Dec 26. PMID: 36581092.
4. Q. Gu and P. Li, ‘Biosynthesis of Vitamins by Probiotic Bacteria’, Probiotics and Prebiotics in Human Nutrition and Health. InTech, Jul. 13, 2016. doi: 10.5772/63117.